Investigation and Evaluation of Cultivation Status of Ligusticum chuanxiong in Sichuan / 中国实验方剂学杂志

Objective::To deeply understand important scientific problems and key technical problems in the cultivation of Chuanxiong, the Chuanxiong cultivation situation of 247 households in 23 towns of 5 counties in Sichuan province were investigated, providing basic data for the standardized cultivation of Chuanxiong. Method::On the basis of reported literatures, a questionnaire survey was conducted on the farmers of cultivating Chuanxiong in main producing areas, field measurements were also preformed, and the cultivation status of Chuanxiong was comprehensively analyzed. Result::The proportion of plain-breeding mainly existed in Pengzhou and Shifang, where per farmer had a small scale of planting areas, was 65%, while the proportion of mountain-breeding mainly existed in Meishan, Qionglai and Dujiangyan, where per proprietor had a large scale of planting areas, was 92%. The planting density and yield of Chuanxiong varied greatly among individuals. The growth period of Chuanxiong in Meishan and Qionglai is about 30 days shorter than that in Pengzhou, Shifang and Dujiangyan. About half of farmers applied base fertilizer and top dressing in spring. The proportion of NPK compound fertilizer input was high (>90%). Chuangxiong has a few diseases and insect pests, the incidence of which in new production areas was obviously lower than that in old production areas. The application of herbicide was not standardized. 52% farmers used Chu cao ling No.1 which was made by agricultural material store owners. The labor cost accounted for the highest proportion (37%) in Chuanxiong cultivation. Conclusion::Now in Sichuan clonal propagated patterns of Chuanxiong were both mountain-breeding and plain-breeding. It is suggested to make clear the differences between mountain-breeding nodes and plain-breeding nodes, and breed high qualities of Chuanxiong nodes. The mechanization research and production of Chuanxiong should be promoted, realizing timely planting and harvesting. Farmers should be guided to increase the application of organic fertilizer, and meanwhile standardize the application of agrochemicals.

A study on the demands and status of the development of specialty nurse in 16 Tibet hospitals / 中国实用护理杂志

Objectives@#To find out the demands and status in quo of the development of specialty nursing and to provide positive suggestions for the further development of specialty nursing in Tibet.@*Methods@#Self-designed questionnaire was adopted to investigate 16 different level hospitals across Tibet.@*Results@#Among the 16 hospitals in which there were altogether 1677 nursing staff and only 11 hospitals had cultivated specialty nurses with a number of 123 in total. The rate of specialty nurses allocated was 7.2%. 9 hospitals expressed the need to develop specialty nurses in nearly future and the number of specialty nurses needed was 577.@*Conclusion@#Tibet should step up the development of specialty nursing, establish and perfect the training method and management system about specialty nurses as soon as possible.

Rationality evaluation and analysis of the overall design of test outline for standardized training of midwives in China / 中华医学教育探索杂志

Objective Through investigating the consistency of clinical first-line midwives actual working requirements and test outline fits, to make analysis on the rationality of the preliminary design test outline to provides evidence for improving the design of test outline for standardized training of midwives. Methods In September 2016,the investigation was conducted using questionnaire based on "Test Outline for Standardized-Training of Midwives (Draft)" among midwives studying in the training base of standardized-training of midwives. 50 questionnaires were distributed, and 49 were recovered, with a recovery rate of 98%. SPSS 16.0 was used to analyze the data and the Cronbach's alpha coefficient was calculated by factor analysis. Results The content reliability of the following units is good such as the overall of Test Outline for Standardized Training of Midwives (Draft)" and "laws and regulations related to maternal and infant health care ","Basic knowledge of medical psychology and ethics", "Basic theory and knowledge of mid-wives", "Clinical manifestations, identification points, common drugs and principles of treatment of the common diseases " and " Specialized skill". Conclusion The overall design of Test Outline for Standardized-Training of Midwives (Draft) is more scientific, and the rational ranking of the examination content is basi- cally consistent with the post competency requirements of the midwives.

Classics textual research and using situation investigation of Tibetan medicine "Zha-xun" / 中国中药杂志

In this article the classics textual research to the origin of "Zha-xun" was carried out, the ethnobotanical research methods, the origin of visits, key informant interviews, sample collection and textual research were applied in the research. The results showed that the hypothesis of Zha-xun"s origin mainly included "source of mine", "source of feces", "source of monkey menstrual blood" in China. There were "source of fossil", "source of the plant secretion" abroad. The authors had interviewed the villagers at origin, herbalists, Tibetan doctors, herb dealers, foreign scholars for a total of 18 people, and collecting 45 batches medicinal materials. According to ancient Tibetan classics textual and Tibetan medicine doctors' views, medicinal materials were divided into the genuine and the substitutes. The genuine was identified as ancient so-called "iron" type "Zha-xun", and the substitute was fecal pellet bonding briquette. According to the field survey and literature research, "source of fossil" more in line with substance of Zha-xun was derived from the rock. As the results, the author believed that Zha-xun was the mixture of organic fossils from the rock seepage with flying squirrel, pika feces. So it is needed to be set up Zha-xun classification standard to evaluate the quality of medicinal materials. Meanwhile, it was necessary to further clarify fecal pellet substitute rationality. Above all, this article clarified the status of the use of Tibetan medicine-"Zha-xun", and laid the foundation of species systematics and quality standards research of "Zha-xun".

Effects of meloxicam on proliferation,migration and expression of PTEN of human colorectal cancer cells / 中国药理学通报

Aim To investigate the effects of meloxi-cam on the proliferation,migration and expression of PTEN of human colorectal cancer LoVo cells.Meth-ods The colony formation test was used to detect the effect of meloxicam on the proliferation of LoVo cells. The cell migration assay was applied to analyze the effect of meloxicam on LoVo cells activity.The RT-PCR assay was used to detect the effect of meloxicam on the mRNA expression of PCNA and PTEN gene. The western blot assay was applied to analyze the effects of meloxicam on the expression of PTEN pro-tein.The recombinant adenovirus and Annexin-V assay were used to testify the relationship between PTEN gene and anti-cancer effect of meloxicam.Results Compared with the control group,meloxicam could in-hibit the colony formation and PCNA protein expression of LoVo cells.At 48 h and 80 μmol·L -1 ,the expres-sion of PCNA protein was reduced to 61 .57% ± 2.81 %(T =7.086,P =0.01 9),the mRNA expres-sion of PTEN gene increased to 1 60.43% ±4.71 %(T=24.244,P =0.002),and the expression of PTEN protein increased to 1 52.63% ±3.33%(T =27.359, P =0.001 ).Results Annexin-V test indicated that the anti-cancer effect of meloxicam was associated with the up-regulated expression of PTEN.Conclusions Meloxicam can inhibit the proliferation and migration of LoVo cells by up-regulating the expression of PTEN.

The Experience of Professor He Jialin in the Treatment on Polycystic Ovary Syndrome / 浙江中医药大学学报

Objective] Investigate the experience of professor He Jialin in the treatment on polycystic ovary syndrome. [Methods]Discuss the clinical experience of professor He Jialin in the treatment on polycystic ovary syndrome from the pathogenesis, treatment, prescription and one case. [Results] Professor He Jialin believes that the disease is caused by kidney deficiency, mixing with phlegmatic block and blood stasis. It can achieve good effect with Bushen Huoxue Huatan method combined with Tiaozhou therapy. [Conclusion] Professor He Jialin's academic thoughts and clinical experience on syndrome differentiation, application method, addition or subtraction of changes provide a more complete mentality and pragmatic value in treating polycystic ovary syndrome.

Effect of 1, 25-dihydroxy vitamin D3 combined with mechanical strain treatment on proliferation, differentiation, and expression of OPG and RANKL in osteoblastic MC3T3-E1 cells / 医用生物力学

Objective To investigate the effect of 1,25-(OH)2-vitamin D3 (VD3) or mechanical strain alone and their combined treatment on proliferation and differentiation of pre-osteoblast MC3T3-E1 cells in vitro, as well as gene and protein expression of osteoprotegerin (OPG) and receptor activator of nuclear factor-кB ligand (RANKL) in those cells. Methods MC3T3-E1 cells were treated with 10 nmol/L VD3, intermitted mechanical strain or with a combination of these two factors. Cell proliferation was assessed with flow cytometry, and alkaline phosphatase (ALP) activity was measured using a fluorometric detection kit. The mRNA expression of ALP, runt-related transcriptional factor 2 (Runx2), OPG, and RANKL genes was determined by real-time PCR. The proteins expression of Runx2, OPG, and RANKL was determined by Western blotting. ResultsVD3 inhibited the proliferation of MC3T3-E1 cells, but the mechanical strain had no effect on cell proliferation. Mechanical strain, VD3, and the combined treatment enhanced the ALP activity of MC3T3-E1 cells as well as the protein expression of Runx2. The effect of combined treatment was less pronounced than the effect of VD3 or mechanical strain alone. Mechanical strain promoted the gene and protein expression of osteoprotegerin (OPG) and increased the ratio of OPG/RANKL. However, the combination of VD3 and mechanical strain led to a decrease in ratio of OPG/RANKL. Conclusions Mechanical strain might be effective in inducing osteogenic differentiation and increasing bone formation. A joint stimulation with VD3 and strain can decrease proliferation and osteogenic differentiation and increase RANKL expression, which might affect bone remodeling. This study supplies some new data, which might be important in theoretical and clinical research of osteoporosis (OP) and other related bone diseases.

Investigation of the anxiety and depression status of patients with paralysis after spinal cord injury and the coping measures / 中国实用护理杂志

Objective To investigate the status of the anxiety and depression in the patients with paralysis after spinal cord injury, and the measures to cope with it. Methods Sixty cases of patients with paralysis after spinal cord injury were evaluated with Self-Rating Anxiety Scale (SAS) and SelfRating Depression Scale (SDS), the results were compared with those of the domestic norm of healthy individuals. Results The scores of patients with paralysis after spinal cord injury were higher than that of domestic norm of healthy individuals. 54 cases had anxious symptom (90.00%), and 37 had depression.The causes led to anxiety and depression mainly came from the suffering of the disease, the influence of the work as well as the study and the cost of the treatment. Conclusions The patients with paralysis after spinal cord injury had mental problems, they need to be interfered with by healthy education and mental nursing in order to promote rehabilitation.

La construcción de la práctica docente como efecto de la intervención institucional en la formación del psicólogo / Building of the teaching practice as an effect of the institutional intervention in psychologists' education

El artículo refiere al proyecto de investigación "Dispositivos analizadores de la formación y práctica profesional del psicólogo", acreditado por PROINPSI. Trasmite el proceso de sistematización de la experiencia en el aula y de varios espacios de reflexión surgidos a partir de ella, de los docentes de la Cátedra I de Psicología Institucional. La Psicología Institucional es entendida como una perspectiva de conocimiento que interpela los imaginarios compartidos que sostienen las prácticas. El proceso de intervención sobre los saberes instituidos permite acompañar a otros en su revisión, a la vez que conocer los propios. Para hacerlo, se construyó en el espacio de trabajos prácticos un dispositivo de Análisis de las Prácticas. Además, esta investigación sistematiza la experiencia de docencia e intervención y provee herramientas para el Análisis de las Prácticas de los docentes, alumnos y profesionales.

The article attempts to convey the process experienced as lecturers of the Institutional Psychology I professorship that is embodied in the PROINPSI sanctioned research project, Education analyzing devices and the psychologist's professional practice, which aims to systematize the experience in the classroom and other spaces of reflection emerged from it. Institutional Psychology is a knowledge perspective that questions the shared imaginary that maintains the practices. The process of intervention allows to accompany in knowledge revision, at the same time as to know the own ones. In order to do it, a device of Analysis of the Practices was constructed. This research also systematize the teaching and intervention experience, and provides consumptions for the Practice Analysis of proffessors.

Investigation and analysis on actuality and demands of scientific researchers in state clinical research facility of TCM / 国际中医中药杂志

Objective To investigate and analysis the actuality and demands of scientific researchers in state clinical research facility of TCM, in order to provide evidences for policy making. Methods All the trainees taken part in the meeting for the training of clinical research method were assigned to answer the self-designed questionnaire. Results Of all these people, 47.58 percent people had senior professional title, 84.14 percent people had doctorate or master degree, 57.24 percent people had participated in project research at provincial or ministerial level as key personnel, 35.17 percent people had participated in a key disease research as directors, 65.52 percent people had taken methodology training of clinical research,30.34% of who trained by evidence-based medicine. The majority of these people had clear understanding in methodology of clinical research, who believed that evidence-based medicine and system evaluation are the most difficult subjects to understand and practice, hoping to learn more about the knowledge on statistics. Conclusion Clinical researchers of state clinical research facility of TCM had sound basis for scientific research, but relatively lacking of key disease research and systematic knowledge of scientific methodology, which needed to be enhanced.

Investigation and Analysis of Patients with Lung Infection After Tracheal Intubation General Anesthesia / 中华医院感染学杂志

OBJECTIVE To know the risk factors about lung infection in patients after tracheal intubation general anesthesia and take control measures.METHODS All the patients with tracheal intubation general anesthesia from Jan to Dec in 2007 were investigated retrospectively.RESULTS Among 2914 operation cases,471 cases were of tracheal intubation general anesthesia and 95 cases were infected(20.17%).The infection rate was 5.38%(24 hours).Sputum culture: G-bacteria accounted for 57.65%,G+ bacteria 28.83%,fungi(13.52%).CONCLUSIONS The infection rate increase with longer intubation time.Mechanical ventilation is a risk factor of lung infection.The measures to control infection include shortening intubation hours,reducing mechanical ventilation and strictly sterilization and isolation.

Effect of Multiple Interventions for Ketogenic Diet on Intractable Epilepsy in Children / 中国康复理论与实践

@#https://www.cjrtponline.com/CN/abstract/abstract1669.shtml

The Survey and Study on HBsAg Carrier at Different Period After Administered Hepatitis B Vaccine / 中国疫苗和免疫

Objective To analyze the positive rate of HBsAg in different population at different periods after widely using Hepatitis B Vaccine and provide strategy for Hepatitis B Control.Methods Using ELISA method to detect the HBsAg carrier in polulation under 18 years old in local area.Results After six year investigating,the HBsAg carrier rate in tested population decreased.For 0-4,4-8,8-12,12-15,15-18 age group,the carrier rate were 3.76% vs 0.30%,4.74% vs 1.39%,5.59% vs 2.52%,8.51% vs 3.03%,and 12.58% vs 2.98% in 2000 and 2006.Conclusion The reduction in carrier rate had a direct relationship with Hepatitis B Vaccine inoculation.Hepatitis B Vaccine had important effect to Hepatitis B control.We should gradually intensify Hepatitis B Vaccine inoculation.It is not only for newborn but also for adult.

Investigation of Outpatient International Prescription Indicators of Rational Drug Use / 药物流行病学杂志

Objective:To understand the present condition of the international prescription indicators of rational drug use for outpatients in our hospital and promote the development of the rational drug use.Method:2694 western medicine prescriptions were randomly selected in our hospital and analyzed according to the reasonable use drug prescription indicators recommended by the WHO.Result:The average number of drugs used by each patient was 2.09;the ratio of using general names was 100.00%;the ratio of using antibiotic was 29.61%,taking up 21.41%of the total drug expenses; the ratio of using injections was 18.22%,taking up 15.98%of the total drug expenses;and the ratio of using basic drugs was 94.86%.The average number of drugs,drugs in general use name ufilization rate and basic drugs utilization rate is stightly better than other local hospitals,but the antibiotic and injection utilization rate is higher.Conclusion:Through the investigation and analysis of the international indicators of rational drug use in our hospital,a theoretical basis was provided for our hospital to draw up a valid intervention measure for further rational drug use.

Necessity of Developing Pharmaceutical Care in the Elderly / 中国药房

OBJECTIVE: To probe into the cognition of the elderly to the safety of drug use and their demand for pharmaceutical care,and to improve pharmaceutical care in the hospital and guarantee the safety of drug use.METHODS: Questionnaires about medication information were designed.315 elderly patients,who were collected from 10 old-age homes of Liaocheng,domestic sickbed department and 5 community medical service stations of Liaocheng Municipal People's Hospital from Oct.2008 to Mar.2009,were involved in study.Investigation data were analyzed statistically using SPSS17.0 software.RESULTS & CONCLUSIONS: Results of study showed that the elderly had not sufficient knowledge towards the safety of drug use,especially drug allergies,side effects of drugs and special population medication.There was significant difference in the understanding of the safety of drug use among the elderly with different education levels,different occupations and different medical insurance patterns.The potential danger of medication is present.They are desirous of acquiring pharmaceutical care.Pharmacists should carry out medicine consultation and popularize pharmaceutical knowledge.They also should provide a comprehensive pharmaceutical care for the elderly people to ensure the safety of drug use in the elderly.

Epidemiological Investigation of Constitutional Types of TCM in 355 Cases of Tumor / 中国中医药信息杂志

Objective To explore the distributed regularity of constitutional types of patients who suffered the gastroenteric carcinomas and lung cancer by epidemiological investigation of constitutional types,in order to analyze the characteristics of different kinds of tumor patients.Methods The standardized Constitution in Chinese Medicine Questionnaire(CCMQ) was answered by 355 patients to evaluate the scores of all kinds of constitutional types.The individual constitutional type was distinguished by the top score method,and the distribution rules of constitutional types in different kinds of tumor patients was analyzed.Results Among the tumor patients,the gentleness type accounted for 17.46 percent,eight pathological constitutions accounted for 82.54 percent.The most two types of pathological constitutions in gastroenteric carcinomas patients were Yang-deficiency and Qi-deficiency,which accounted for 23.98 percent and 23.39 percent respectively,while the majority of that in lung cancer patients were Qi-deficiency(42.93%) and Yang-deficiency(15.76%).Conclusion The patients suffering from different kinds of tumor have different constitution characteristics.It is a better idea to integrate the constitution analysis with syndrome differentiation treatment in clinical practice.

Analysis of Factors Relevant to the Onset of Eczema in 479 Infants in Taiyuan / 中国中医药信息杂志

0.05). 73.96% of eczema were taken place at the age of 1～6 months, 13.02% were at the age of 6 months to 2 years, and 13.61% were at the age of 2～3 years. The incidence of eczema is also relevant to feeding patterns, which is 62.23%, 23.08% and 14.79% respectively by breast-feeding, mixed feeding and artificial feeding. Some other factors that relevant to the onset of eczema also have been found in the study, such as constitution, weather, genetic background, and so on. Conclusion Feeding pattern, genetic background and some other factors were relevant to the onset of eczema.

Protective effects of propofol on renal injury during liver ischemia-reperfusion / 中国康复理论与实践

@#ObjectiveTo investigate the remote renal injury after liver ischemia-reperfusion(I/R) and the renal protection afforded by propofol.Methods 72 male SD rats were randomly divided into three groups:normol control group, I/R group and propofol group .The animals were killed after 60 minutes ischemia of liver followed by reperfusion for 4 h,2 h. Blood urea nitrogen (BUN) and creatinine (Cr) were detected,and renal histopathologic lesion were observed.ResultsIn I/R group,the serum level of BUN and Cr increased significantly compared with the baseline before liver I/R,while propofol could decrease the serum level of BUN and Cr significantly.ConclusionPropofol can reduce the renal injury during liver I/R.

Epidemiological investigation of constitutional types of Chinese medicine in general population:Base on 21,948 epidemiological investigation data of nine provinces in China / 中华中医药杂志

Objects:To describe the distribution regularity of constitutional types of Chinese medicine in general population and analysis the characteristics of different social demography population through epidemiological investigation of constitutional types of Chinese medicine in general population.Methods:Using 21,948 cases large sample data of Chinese medical constitution cross-section survey from general population of nine provinces and municipalities(Jiangsu,Anhui,Gansu,Qinghai,Fujian,Beijing,Jilin,Jiangxi and He’nan),from December 2005 to January 2007.8,448 samples in accord with sample data from 1% nationwide population survey in 2005,which could representative the general population of China were randomly selected.Using the standardized Constitution in Chinese Medicine Questionnaire(CCMQ) to evaluation the scores of all kinds of Constitutional types(Gentleness type,Qi-defi ciency type,Yang-defi ciency type,Yin-defi ciency type,Phlegm-wetness type,Wet-heat type,Blood-stasis type,Qi-depression type,Special diathesis type).Application Discriminant Analysis to distinguish the individual Constitutional types,and analysis the distribution regularity of constitutional types of Chinese medicine in general population.Variables grouped by social demographic,use ?2 test to compare the differences in each sub-group’s constitution composition.Results:In the general population in China,Gentleness type accounted for 32.14 percent,eight pathological constitutions accounted for 67.86 percent,and the former three types of eight pathological constitutions were Qi-defi ciency type,Wet-heat type and Yang-deficiency type,which accounted for 13.42 percent,9.08 percent and 9.04 percent respectively.The composition ratio of constitutional types in different geographical,gender,age,marital status,occupation and education level were different,and the difference was signifi cant(P

Study of the relationship between carotid atherosclerosis and progressing stroke / 中国康复理论与实践

@#ObjectiveTo investigate the relationship between carotid atherosclerosis and progressing stroke.Methods103 patients with acute cerebral infarction within the first 24 hours from onset were tested with carotid color doppler ultrasonography during the first week from admission. Univariate and multiple logistic regression analyses were performed to examine the relationship between carotid intima media thickness (IMT), plaque structure, the degree of artery stenosis and the early deterioration of cerebral infarction.ResultsPrevalence of carotid plaque and thickness of IMT in patients with progressing stroke were higher than that in non progressing patients. In logistic regression, presence of carotid plaque was independent predictors of progressing stroke. Plaque size, extent of artery stenosis and IMT were not included in the regression model.ConclusionPlaque structure and its chemical feature may be the cause of progressing stroke.